Stereochemistry – Mechanisms of Organic Reactions

Syllabus

1. 1. Introduction
   1. History – background
   2. Stereochemical presentations
   3. Classification of isomers
   4. The chiral center
2. Determination of Configuration
   1. Carbohydrates
   2. Aminoacids
   3. Sequence rule
3. Symmetry
   1. Introduction
   2. Symmetry Elements, Operation, Symbols
   3. Symmetry Point Groups
4. Configuration
   1. Methods for the Determination of Relative and Absolute Configuration
   2. Chiroptical, Spectroscopic and other Physical Methods
5. Conformation
   1. Conformation of Ethane and Butane
   2. Physical and Spectral Properties of Diastereomers and Conformers
   3. Conformation and Reactivity
6. Separation and Analysis of Stereoisomers
7. Asymmetric Synthesis
8. Chiroptical Properties
9. Stereochemistry of Certain Enzymatic Reactions.

Learning Outcomes

To gain advanced knowledge in stereochemistry